Genetic associations with IBM

Genetic associations with Achilles tendinopathy.

In this issue of Rheumatology, Posthumus et al. [1] report the results of a genotype association study in patients with Achilles tendon pathology vs normal Achilles tendons. The main finding is that individuals who carry a particular single nuclear polymorphism (SNP; specifically, the TT genotype of the GDF5 rs143383 variant) have twice the risk of developing Achilles tendon pathology compared ...

Ethnic-specific genetic associations with pulmonary tuberculosis.

Several susceptibility-associated genetic polymorphisms have been proposed to explain differential susceptibility to tuberculosis (TB) disease progression in different populations. Here, polymorphisms in the natural resistance-associated macrophage protein 1 (NRAMP1), vitamin D receptor, tumor necrosis factor-alpha, interleukin (IL)-1, and IL-10 genes were evaluated in 358 Cambodian patients wi...

IBM DB2 with BLU Acceleration

Furthermore, BLU Acceleration is built directly into the DB2 kernel (see Figure 1). It is not just an additional feature; it is an integral part of DB2 and every part of DB2 is aware of it. BLU Acceleration still uses the same storage unit of pages, the same buffer pools, and the same backup and recovery mechanisms, so BLU Acceleration tables can coexist with traditional row tables in the same ...

Statistical Analysis of Genetic Associations

ZAYKIN, DMITRI V. Statistical Analysis of Genetic Associations (Advisor: Bruce S. Weir) There is an increasing need for a statistical treatment of genetic data prompted by recent advances in molecular genetics and molecular technology. Study of associations between genes is one of the most important aspects in applications of population genetics theory and statistical methodology to genetic dat...

Genetic associations in myasthenia gravis